Figure 3.

Histopathological analysis of treated and untreated wounds at D7. (A) Five-μm sections stained by HE, showing complete closure of the wound with a uniform thickness in most of the copaiba-treated samples analyzed compared to the corticoid-treated and control samples. (B) Inflammatory scores presented no significant differences between groups on this day. (C) Copaiba-treated wounds presented an advanced reepithelization stage. The corticoid-treated group still revealed a poor reepithelization performance on this day (original magnification ×200 and ×1000). One-way ANOVA and Tukey’s post hoc tests (n = 15) (* p < 0.05).