Methodological summary of the experiment (a) On day zero (D0), a traumatic ulcer in the ventral surface of tongue was induced with a standard punch biopsy technique (diameter 3 mm). (b) Treatments were administrated 12 h post wounding, and the next two days by oral gavage. (c) On D3, D7 and D15, samples were collected for clinical, histopathological and histochemical analysis. Blood was collected by cardiac puncture for a biochemical assessment of liver and kidneys functions at D3 and D7. (d) The different analyses were performed and (e) the data were tabulated for a comparative statistical analysis. The results are expressed as the mean ± standard error of the mean.