Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 16;21(10):3530. doi: 10.3390/ijms21103530

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Validation for the detected somatic variants by CHIPS and Sanger sequencing. (A) Summary of validation results. (B) CHIPS technology assay. Red arrow head shows cleaved heteroduplexes. U: uncut C: cut by CEL nuclease. (C) Aligned reads visualized by Integrative Genomic Viewer (IGV) at the detected somatic variant positions. (D) and (E) Electropherograms of Sanger sequencing of the detected somatic variants in blood and tumor samples. (F) Ratio of validated and not validated variants in category 1, 2, and 3.