Table 1.

Summary of the validated mutations.

Gene	Position (hg38)	DNA	Mutation Type	Protein	dbSNP	ClinVar	COSMIC
FBXW7	chr4:152326214	NM_033632.3:c.1436G > A	missense	NP_361014.1:p.Arg479Gln	rs866987936	376419	COSM1154291; COSM22974; COSM447498; COSM447499; COSM6847976: COSM94297
MAP3K1	chr5:56882328	NM005921.1:c.3138C > T	missense	NP_005912.1:p.Ser1043Phe	-	-	COSM6889390
NRG1	chr8:32631387	NM_13960.4:c.502+14502C > G	intron variant	-	-	-	-
NRG1	chr8:32631557	NM_13960.4:c.502+14672C > G	intron variant	-	-	-	-
CDKN2A	chr9:21974793	NM_058197.4:c.35C > T	missense	NP_478104.2:p.Ser12Leu	rs141798398	236988	COSM6985693; COSM6985694; COSM6985695