Figure 6.

Acellular capillaries in the retinas of STZ-induced diabetic mice (A) Representative images of acellular capillaries and degeneration in retinal capillary beds of non-diabetic, diabetic, and SR1001 treated diabetic C57BL/6 mice (scale bars of all images = 10 μm, which is a visual indicator of the size of the representative images). Red arrows highlight acellular capillaries. (B) Quantification of acellular capillaries within a 1.10 mm² area of each retina of non-diabetic (white square), diabetic (black square), and SR1001 treated diabetic (grey circle) C57BL/6 mice. Each data point represents an individual retina from 4 different mice. Error bars represent the SEM, and p-value was first equated by two-way ANOVA analysis and then an unpaired t-test with Tukey’s post-hoc analysis, wherein * p < 0.01. All samples were collected 8 months after diabetic conditions were confirmed.