ERAD | Endoplasmic reticulum-associated degradation |
LC–MS/MS | Liquid chromatography–mass spectrometry/mass spectrometry |
IDR | Intrinsically disordered region |
LFQ | Label-free quantification |
PSM | Peptide-spectrum match |
α-1AT | α1-antitrypsin |
NHK | Null Hong Kong variant of α1-antitrypsin |
Ri | Ribophorin I |
BACE | Beta-secretase |
E1-KO | EDEM1 knock-out |
∆-EDEM1 | EDEM1 mutant lacking the IDR |
CNX | calnexin |
UPR | Unfolded protein response |