Table 2.
Relationship between SRPX2 Expression and Clinicopathological Parameters.
| SRPX2 Expression | |||
|---|---|---|---|
| Parameters | − (%) | + (%) | p Value * |
| Gender | |||
| Male | 61 (68.5) | 28 (31.5) | |
| Female | 55 (76.4) | 17 (23.6) | 0.2938 |
| Age | |||
| <65 | 54 (75) | 18 (25) | |
| >65 | 62 (69.7) | 27 (30.3) | 0.4844 |
| Site | |||
| Tongue | 60 (66.7) | 30 (33.3) | |
| Gingiva | 42 (80.8) | 10 (19.2) | |
| Buccal mucosa | 7 (70) | 3 (30) | |
| Other | 7 (77.8) | 2 (22.2) | 0.3305 |
| Histology | |||
| Well | 57 (75) | 19 (25) | |
| Moderately, Poorly | 59 (69.4) | 26 (30.6) | 0.4839 |
| T classification | |||
| T1-T3 | 81 (74.3) | 28 (25.7) | |
| T4 | 35 (67.3) | 17 (32.7) | 0.3554 |
| Clinical stage | |||
| I-II | 79 (75.2) | 26 (24.8) | |
| IV | 37 (66.1) | 19 (33.9) | 0.2688 |
| Nodal metastasis | |||
| Negative | 91 (77.1) | 27 (22.9) | |
| Positive | 25 (58.1) | 18 (41.9) | 0.0280 |
| MVD | 25.128 ± 14.741 | 33.109 ± 23.841 | 0.0111 |
| LVD | 20.245 ± 13.894 | 27.136 ± 19.583 | 0.0129 |
The relationship between expression of sushi repeat containing protein X linked-2 (SRPX2) and each factor was calculated by Fisher’s exact test or chi-square test. The differences of the microvessel density (MVD) and lymphovessel density (LVD) among groups were analyzed by unpaired parametric t-test. MVD and LVD were Means ± S.D. (standard deviation), each S.D. was less than 10% in all cases. T classification and clinical stage were classified according to the TNM classification.* p value < 0.05 was regarded as statistically significant.