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. 2020 May 12;21(10):3407. doi: 10.3390/ijms21103407

Table 1.

Evaluated values of ENaC’s trafficking rates in the presence and absence of 100 nM insulin with and without 1 µM aldosterone treatment for 20 h.

Insulin ALDO Insertion
kI (h−1)
Endocytosis
kE (h−1)
Recycling
kR (h−1)
Degradation
kD (h−1)
(+) (+) 1.57 ± 0.06 # 2.12 ± 0.20 NS 6.42 ± 0.99 ## 3.16 ± 0.12 #
(−) 0.47 ± 0.08 1.99 ± 0.74 3.23 ± 0.75 4.59 ± 0.40
(−) (+) 0.24 ± 0.02 NS 2.45 ± 0.42 * 3.62 ± 0.10 * 5.20 ± 0.46 NS
(−) 0.21 ± 0.01 5.22 ± 0.45 2.50 ± 0.13 5.62 ± 0.19

ALDO, aldosterone. # significantly different between ALDO (+) and (−) in Insulin (+) at p < 0.01 (n = 5). ## significantly different between ALDO (+) and (−) in Insulin (+) at p < 0.05 (n = 5). * significantly different between ALDO (+) and (−) in Insulin (−) at p < 0.005 (n = 4). NS no significant difference between ALDO (+) and (−) in Insulin (+) (n = 5), and ALDO (+) and (−) in insulin (−) (n = 4). Results shown in Table 1 are expressed as the mean ± standard error (S.E.).