Table 5.
Group 1. Multivariate regression analysis showing factors associated with change in composite cognitive score
| Predictor variable | Change in total cognitive z-score | |
| B coefficient | P value | |
| Constant | −1.689 | 0.781 |
| Group (antidopaminergic takers vs non-antidopaminergic takers) | −1.244 | <0.001 |
| Age | 0.046 | 0.071 |
| Gender | 0.083 | 0.493 |
| CAG repeat length | 0.094 | 0.430 |
| DBS | −0.008 | 0.008 |
| TFC | −0.039 | 0.586 |
| Time since diagnosis | 0.020 | 0.619 |
| UHDRS total motor score | −0.003 | 0.813 |
| Depression (PBA) | −0.012 | 0.659 |
| Irritability (PBA) | −0.059 | 0.087 |
| Apathy (PBA) | 0.030 | 0.445 |
| ISCED | −0.155 | 0.183 |
ISCED, The International Standard Classification of Education; CAG, cytosine-adenine-guanine.
DBS, disease burden score; PBS, problems behavioural assessment; TFC, total functional capacity; UHDRS, Unified Huntington Disease Rating Scale.