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. 2020 Mar 12;91(6):580–585. doi: 10.1136/jnnp-2019-322663

Table 1.

Baseline characteristics of all patients with a first-in-study-period intracerebral haemorrhage ascertained in Oxford Vascular Study (2002–2018) stratified by haematoma location

Total
(n=255)*
Lobar ICH
(n=109)
Non-lobar ICH
(n=144)
P value
Age (mean/SD) 75.5/13.1 76.4/12.0 74.8/13.8 0.34
Male sex 126 (49.4) 50 (45.9) 76 (52.8) 0.28
NIHSS (median, IQR)† 8 (4–16) 9 (4–17) 8 (4–15) 0.94
Medical history
 Previous TIA or ischaemic stroke 73 (28.9) 39 (35.8) 34 (23.6) 0.03
 MI or peripheral vascular disease 21 (8.3) 15 (13.8) 6 (4.2) 0.006
 Hypertension 156 (61.2) 58 (53.2) 97 (67.4) 0.02
 Diabetes mellitus 36 (14.1) 14 (12.8) 22 (15.3) 0.58
 Hyperlipidaemia 59 (23.1) 24 (22.0) 35 (24.3) 0.67
 Atrial fibrillation 57 (22.4) 24 (22.0) 33 (22.9) 0.87
 History of smoking‡ 116 (47.0) 47 (45.2) 69 (48.9) 0.56
 Current smoker§ 24 (9.7) 10 (9.5) 14 (9.9) 0.92
Premorbid medication
 Antithrombotics¶ 122 (47.8) 55 (50.5) 66 (45.8) 0.47
 Anticoagulants 54 (21.2) 27 (24.8) 27 (18.8) 0.25
 Antiplatelet treatment 73 (28.6) 30 (27.5) 42 (29.2) 0.77
 Antihypertensive treatment 126 (49.4) 48 (44.0) 77 (53.5) 0.14
 Statins 66 (25.9) 36 (33.0) 29 (20.1) 0.02
Antithrombotics at discharge** (n=143) (n=60) (n=83)
 Anticoagulants 1 (0.7) 1 (1.7) 0 (0) 0.24
 Antiplatelet treatment 7 (4.9) 5 (8.3) 2 (2.4) 0.11

Numbers are presented as n (%) unless otherwise stated.

*n=2 with unknown location due to out-of-area death and no imaging was not accessible.

†Data missing for n=6.

‡Data missing for n=8.

§Data missing for n=7.

¶n=5 patients on both anticoagulant and antiplatelet drugs (n=2 for lobar and n=3 for non-lobar).

**Excluding patients that died prior to discharge.

ICH, intracerebral haemorrhage; MI, myocardial infarction; NIHSS, National Institute of Health Stroke Scale; TIA, transient ischaemic attack.