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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Sirtuin inhibitors (SIRTi) inhibitors used in this study. The 33 SIRTi tested against T. cruzi sirtuins, TcSir2rp1 and TcSir2rp3, classified based on its chemical structure.