Table 1.
Compounds | TcSir2rp1 | TcSir2rp3 |
---|---|---|
IC50 ± SD (µM) a | IC50 ± SD (µM) a | |
8 | ND | 18.8 ± 5.34 |
12 | ND | 14.3 ± 6.06 |
13 | ND | 18.5 ± 1.97 |
15 | 32.4 ± 7.88 | ND |
17 | 25.5 ± 4.73 | ND |
31 | ND | 16.3 ± 9.54 |
32 | ND | 16.4 ± 6.70 |
a Sirtuin activity was determined 4 h after incubation.