Figure 2.

Exogenous miR-29a injection significantly reverses the markers assessing hepatic inflammation and fibrosis. (A–D) Serum GOT, GPT, GOT/GPT ratio, and total bilirubin. mRNA expression level of (E) colla1, (F) Il1b, and (G) tgfb1. β-actin level is used as the normalization control. N = 5–9 was used for each group. Data are expressed as mean ± SE. * p < 0.05 between the groups. Sham, a sham surgery only. BDL, a bile duct ligation operation only. BDL + scramble, mice received exogenous scramble injection after BDL. BDL + miR-29a, mice received exogenous miR-29a injection after BDL. GOT: glutamic oxaloacetic transaminase. GPT: glutamic-pyruvic transaminase.