Table 1.
Parameter | Time Point | Sham | BDL | BDL + Scramble | BDL+miR-29a |
---|---|---|---|---|---|
Body Weight (g) | Day 0 | 23.25 ± 0.51 | 23.26 ± 0.29 | 24.23 ± 0.32 | 24.46 ± 0.35 |
Day 7 | 23.93 ± 0.53 | 18.72 ± 0.35 a | 18.77 ± 0.23 a | 18.82 ± 0.27 a | |
Body Weight Gain (%) | Day 7 | 2.9 ± 0.52 | −19.48 ± 1.17 a | −22.52 ± 0.96 a | −22.97 ± 1.39 a,b |
Liver Weight (g) | Day 7 | 1.19 ± 0.07 | 1.36 ± 0.04 a | 1.21 ± 0.06 | 1.22 ± 0.05 |
Liver/Body Weight (%) | Day 7 | 4.94 ± 0.21 | 7.25 ± 0.13 a | 6.44 ± 0.26 a,b | 6.49 ± 0.18 a,b |
Data collected from seven to ten mice each group expressed as mean ± SE; a, p < 0.05 versus sham; b, p < 0.05 versus BDL. BDL: bile duct ligation.