Table 3.
Characteristics of index tumors in patients with multifocal, multicentric, or unicentric breast cancer.
| Variable | Multifocal n = (%) | Multicentric n = (%) | Unicentric n = (%) | p Value | |
|---|---|---|---|---|---|
| Age (years) | Mean Median Minimum Maximum |
60 61 24 81 |
60 57 48 83 |
60 61 26 87 |
NS |
| Gender | Female Male |
31 (100%) 0 (0%) |
6 (100%) 0 (0%) |
173 (96.65%) 6 (3.35%) |
0.523 |
| Laterality | Left-sided Right-sided Bilateral |
16 (51.61%) 14 (45.16%) 1 (3.23%) |
4 (66.67%) 2 (33.33%) 0 (0%) |
113 (64.57%) 59 (33.71%) 3 (1.71%) |
0.728 |
| Grade of differentiation | G1 G2 G3 |
3 (9.68%) 23 (74.19%) 5 (16.13%) |
0 (0%) 4 (66.67%) 2 (33.33%) |
30 (18.07%) 92 (55.42%) 44 (26.51%) |
0.605 |
| Nodal metastasis | pN0 pN1 pN2 pN3 |
18 (58.06%) 12 (38.71%) 1 (3.23%) 0 (0%) |
4 (66.67%) 1 (16.67%) 1 (16.67%) 0 (0%) |
108 (61.71%) 52 (29.71%) 10 (5.71%) 5 (2.86%) |
0.698 |
| Molecular subtype | Luminal A Luminal B Triple negative HER2+ |
19 (61.29%) 6 (19.35%) 5 (16.13%) 1 (3.23%) |
6 (100%) 0 (0%) 0 (0%) 0 (0%) |
70 (46.67%) 51 (34%) 18 (12%) 11 (7.33%) |
0.266 |
P = by histopathological examination; ER = estrogen receptor, PR = progesterone receptor, HER2 = Human Epidermal Growth Factor Receptor 2; IHC = immunohistochemical.