Table 2.
1H and 13C NMR spectroscopic data for compounds 1–3 (600 MHz, acetone-d6).
| Position | 1 | 2 | 3 | |||
|---|---|---|---|---|---|---|
| δH, mult (J in Hz) | δ C | δH, mult (J in Hz) | δ C | δH, mult (J in Hz) | δ C | |
| 2 | 3.15, q (6.10, 11.31) | 52.1 | 3.31, brs | 50.6 | 3.24, m | 53.7 |
| 3 | 1.61, qd (4.57, 6.10) | 42.3 | 1.69, td (3.74, 7.87) | 43.8 | 1.66, qd (4.17, 6.72) | 43.7 |
| 4 | 5.08, overlap | 46.9 | 4.71, dd (3.74) | 49.9 | 4.78, t (7.82) | 49.9 |
| 4a | - | 123.1 | - | 121.3 | - | 123.6 |
| 5 | 7.13, d (7.50) | 128.8 | 7.10, d (1.39) | 131.7 | 7.07, d, (7.60) | 129.4 |
| 6 | 6.47, td (1.02, 7.43) | 116.4 | 6.52, td (1.39, 7.78) | 117.1 | 6.50, m | 117.0 |
| 7 | 6.89, m | 128.3 | 6.92, m | 128.5 | 6.89, m | 128.2 |
| 8 | 6.52, d (7.43) | 114.2 | 6.54, d (7.78) | 114.8 | 6.53, d (8.12) | 114.6 |
| 8a | - | 145.1 | - | 146.0 | - | 145.7 |
| 9 | 1.54, m | 37.8 | 1.51, m | 34.8 | 1.62/1.55, m | 37.0 |
| 10 | 1.54/1.45, m | 18.9 | 1.43, m | 18.9 | 1.43, m | 19.2 |
| 11 | 0.93, t (7.18) | 14.5 | 0.94, m, overlap | 14.5 | 0.92, m, overlap | 14.5 |
| 12 | 1.32, m | 20.3 | 1.51/1.38, m | 20.1 | 1.50, m | 23.0 |
| 13 | 0.98, t (7.42) | 12.2 | 0.96, m, overlap | 12.4 | 0.95, m, overlap | 10.4 |
| 15 | - | 159.1 | - | 158.2 | - | 159.5 |
| NH-1 | 5.08, m, overlap | - | 4.96, s | - | 4.88, s | - |
| NH-14 | 5.64, d (9.74) | - | 5.74, d (6.69) | - | 5.59, d (7.78) | - |
| NH2-16 | 5.08, m, overlap | - | 5.01, s | - | 5.09, s | - |