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. 2020 May 21;21(10):3648. doi: 10.3390/ijms21103648

Table 1.

Doses of EDs normalized to the same unit of measurement and their effects on human thyroid cell monolayers.

Human
Thyroid Carcinoma
FTC-238 Cells
Male Donor
[15]
8505C Human Thyroid Cells
Female Donor
[16]
KAT5 Human
Thyroid Carcinoma Cells
Female Donor
[21]
TT Human Thyroid Cell Line
Female Donor
[19]
Polycyclic aromatic hydrocarbons (PAH)
µg/L
Benz(a)anthracene (BAA) 220
↑ cell proliferation
Benzo[a]pyrene (BAP) 252.31
↓TPO
250
↑ cell proliferation
Benzo[k]fluoranthene (BKF) 0.25–2.52
↓TPO
250
↑ cell proliferation
Dibenzo[a,h]anthracene (DahA) 278.34–2783.46
↑TPO
3-methylchloranthracene 0.02–214.69
↓TPO
Pyrene 0.20–20.22
↓TPO
Heavy Metals
µg/L
Cadmium (Cd) 160
cytotoxic effect
560–1120
arrest of cell growth in the G0/G1 phase
Copper (Cu) 90
cytotoxic effect
Nickel (Ni) 90
cytotoxic effect
Zinc (Zn) 100
cytotoxic effect
MeHg 107.81–4312.54 cytotoxic effect