CNS |
central nervous system |
ACKRs |
atypical receptors for chemokines |
AA |
amino acids |
ECM |
extracellular matrix |
GAGs |
glycosaminoglycans |
GPCR |
G-protein-coupled receptor |
CKRs |
chemokine receptors |
MAPK |
mitogen-activated protein kinase |
PI3K |
phosphoinositide 3-kinase |
PLC |
phospholipase C |
cCKRs |
conventional chemokine receptors |
IL-1 |
interleukin 1 |
TNF-α |
tumor necrosis factor alpha |
LPS |
lipopolysaccharides |
SDF-1 |
stromal derived factor 1 |
BM |
bone marrow |
hNPCs |
human neural progenitor cells |
NK |
natural killer |
BBB |
blood–brain barrier |
PDGF |
platelet-derived growth factor |
VCAM-1 |
vascular cell adhesion molecule-1 |
FGF |
fibroblast growth factor |
MMPs |
matrix metalloproteinases |
GROα |
growth-related oncogene alpha |
ENA-78 |
epithelial neutrophil-activating protein-78 |
GCP-2 |
granulocyte chemotactic protein 2 |
NAP-2 |
neutrophil-activating protein-2 |
IL-8 |
interleukin 8 |
VEGF |
vascular endothelial growth factor |
IFN |
interferon |
PF4 |
platelet factor-4 |
MIG |
monokine induced by interferon-γ |
IP-10 |
interferon-γ inducible protein-10 |
I-TAC |
interferon-γ inducible T cell chemoattractant |
BRAK |
breast-and-kidney-expressed chemokine |
ERK |
extracellular-signal-regulated kinase |
NO |
nitric oxide |
eNOS |
endothelial nitric oxide synthase |
DCs |
dendritic cells |
LEC |
liver-expressed chemokine |
MTN-1 |
monotactin-1 |
SLC |
secondary lymphoid-tissue chemokine |
TAM |
tumor-associated macrophages |
TGF-β |
transforming growth factor |
MT-1 MMP |
membrane type 1-matrix metalloproteinase |
TANs |
tumor associated neutrophils |
HIF-1α |
hypoxia-inducible factor 1-alpha |
CAF |
cancer-associated fibroblasts |
TME |
tumor microenvironment |
TARC |
thymus and activation-regulated chemokine |
MDC |
macrophage-derived chemokine |
WHO |
World Health Organization |
LGG |
low-grade infiltrating gliomas |
HGG |
high-grade gliomas |
GBM |
glioblastoma multiforme |
PrGBM |
primary glioblastoma multiforme |
ScGBM |
secondary glioblastoma multiforme |
IDH1/2 |
isocitrate dehydrogenase 1/2 |
LOH |
loss of heterozygosity |
EGFR |
epidermal growth factor |
ENM |
extra-neural metastases |
FGF |
fibroblast growth factor |
EGF |
epidermal growth factor |
NF-kB |
nuclear factor-kappa B |
CSF |
cerebrospinal fluid |
VM |
vascular mimicry |
AAT |
antiangiogenic therapies |
EMT |
epithelial–mesenchymal transition |
Tregs |
regulatory T-cells |
MDSCs |
myeloid-derived suppressor cells |
MIF |
macrophage migration inhibitory factor |
AP-1 |
activator protein 1 |
uPA |
urokinase plasminogen activator |
RANTES |
regulated on activation, normally T-expressed, and secreted |
DARC |
Duffy antigen for chemokines |
CCX-CKR |
ChemoCentryx chemokine receptor |
NSCLC |
non-small cell lung cancer |
HCC |
hepatocellular carcinoma |
CCRL2 |
chemokine CC-motif receptor-like 2 |
CRAM |
chemokine receptor on activated macrophages |
PITPNM3 |
phosphatidylinositol transfer protein 3 |
Pyk2 |
proline-rich tyrosine kinase 2 |
CEA |
carcinoembryonal antigen |
NSE |
neuron-specific enolase |
ELISA |
sandwich enzyme-linked immunosorbent assay |