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. 2020 May 24;21(10):3704. doi: 10.3390/ijms21103704
CNS central nervous system
ACKRs atypical receptors for chemokines
AA amino acids
ECM extracellular matrix
GAGs glycosaminoglycans
GPCR G-protein-coupled receptor
CKRs chemokine receptors
MAPK mitogen-activated protein kinase
PI3K phosphoinositide 3-kinase
PLC phospholipase C
cCKRs conventional chemokine receptors
IL-1 interleukin 1
TNF-α tumor necrosis factor alpha
LPS lipopolysaccharides
SDF-1 stromal derived factor 1
BM bone marrow
hNPCs human neural progenitor cells
NK natural killer
BBB blood–brain barrier
PDGF platelet-derived growth factor
VCAM-1 vascular cell adhesion molecule-1
FGF fibroblast growth factor
MMPs matrix metalloproteinases
GROα growth-related oncogene alpha
ENA-78 epithelial neutrophil-activating protein-78
GCP-2 granulocyte chemotactic protein 2
NAP-2 neutrophil-activating protein-2
IL-8 interleukin 8
VEGF vascular endothelial growth factor
IFN interferon
PF4 platelet factor-4
MIG monokine induced by interferon-γ
IP-10 interferon-γ inducible protein-10
I-TAC interferon-γ inducible T cell chemoattractant
BRAK breast-and-kidney-expressed chemokine
ERK extracellular-signal-regulated kinase
NO nitric oxide
eNOS endothelial nitric oxide synthase
DCs dendritic cells
LEC liver-expressed chemokine
MTN-1 monotactin-1
SLC secondary lymphoid-tissue chemokine
TAM tumor-associated macrophages
TGF-β transforming growth factor
MT-1 MMP membrane type 1-matrix metalloproteinase
TANs tumor associated neutrophils
HIF-1α hypoxia-inducible factor 1-alpha
CAF cancer-associated fibroblasts
TME tumor microenvironment
TARC thymus and activation-regulated chemokine
MDC macrophage-derived chemokine
WHO World Health Organization
LGG low-grade infiltrating gliomas
HGG high-grade gliomas
GBM glioblastoma multiforme
PrGBM primary glioblastoma multiforme
ScGBM secondary glioblastoma multiforme
IDH1/2 isocitrate dehydrogenase 1/2
LOH loss of heterozygosity
EGFR epidermal growth factor
ENM extra-neural metastases
FGF fibroblast growth factor
EGF epidermal growth factor
NF-kB nuclear factor-kappa B
CSF cerebrospinal fluid
VM vascular mimicry
AAT antiangiogenic therapies
EMT epithelial–mesenchymal transition
Tregs regulatory T-cells
MDSCs myeloid-derived suppressor cells
MIF macrophage migration inhibitory factor
AP-1 activator protein 1
uPA urokinase plasminogen activator
RANTES regulated on activation, normally T-expressed, and secreted
DARC Duffy antigen for chemokines
CCX-CKR ChemoCentryx chemokine receptor
NSCLC non-small cell lung cancer
HCC hepatocellular carcinoma
CCRL2 chemokine CC-motif receptor-like 2
CRAM chemokine receptor on activated macrophages
PITPNM3 phosphatidylinositol transfer protein 3
Pyk2 proline-rich tyrosine kinase 2
CEA carcinoembryonal antigen
NSE neuron-specific enolase
ELISA sandwich enzyme-linked immunosorbent assay