OA	Osteoarthritis
WHO	World Health Organization
IL	Interleukin
TNF	Tumor necrosis factor
MMPs	Matrix metalloproteinases
NO	Nitric oxide
PGE2	Prostaglandin E2
COX-2	Cyclooxygenase 2
TKA	Total knee arthroplasty
ACR	American College of Rheumatology
3D	Three-dimensional
Col	Collagen
E2	17β-estradiol
IHC	Immunohistochemistry
ER	Estrogen receptor
AR	Androgen receptor
FACS	Fluorescence-activated cell sorting
TGF	Transforming growth factor
FGF-2	Fibroblast growth factor-2
aCGH	Array-based comparative genomic hybridization
FISH	Fluorescent in situ hybridization
THR	Total hip replacement
DMEM	Dulbecco’s modified Eagle eedium
TNAP	Tissue non-specific alkaline phosphatase
ELISA	Enzyme-linked immunosorbent assay
MCP	Monocyte Chemoattractant Protein
RT-PCR	Real-time C-reactive Protein
TMJ	Temporomandibular joint
FLS	Fibroblast-like synoviocytes
sGAGs	Sulphated glycosaminoglycans
HGF	Hepatocyte growth factor
ALP	Alkaline phosphatase
BMD	Bone mineral density
μCT	Micro-computed tomography
BV/TV	Trabecular bone volume
Tb.N	Trabecular number
Tb.Th	Trabecular thickness
MV	Medullary volume
cBV/TV	Cortical bone volume per total tissue volume
ADITT	Angular degree of internal tibial torsion
CSA	Cross sectional area
Frzb	Frizzled-related protein
OARSI	Osteoarthritis Research Society International
MMT	Medial meniscectomy
DMM	Destabilization of the medial meniscus
EGFR	Epidermal growth factor receptor
NMR	Nuclear magnetic resonance
OPLS-DA	Orthogonal partial least squares-discriminant analysis
PUFAs	Polyunsaturated fatty acids
n-6	Omega-6
n-3	Omega-3
GC-FID	Gas chromatography with flame-ionization detection
hCRP	Human C-reactive protein
CETP	Cholesteryl ester transfer protein
MIA	Monosodium iodoacetate
IGF1	Insulin-like growth factor-1
IGFR1	Insulin-like growth factor type 1 receptor
IGFBP3	Insulin-like growth factor binding protein-3
CFA	Complete Freund’s adjuvant
iNOS	Inducible nitric oxide synthase
MD	Mineral density
ACL	Anterior cruciate ligament
ECM	Extracellular matrix
PRP	Platelet-rich plasma
PRISMA	Preferred Reporting Items for Systematic Reviews and Meta-Analyses
DNA	Deoxyribonucleic acid
OC	Osteocalcin
OP	Osteoprotegerin
ACAN	Aggrecan
VDR	Vitamin D receptor
M-CSF	Macrophage colony-stimulating factor
COMP	Cartilage oligomeric matrix protein
NSAIDs	Non-steroidal anti-inflammatory drugs
2D	Two-dimensional
MIG	Monokine induced by gamma interferon
PDIA3	Protein disulfide isomerase A3
LIF	Leukemia inhibitory factor
MIF	Macrophage migration inhibitory factor
GRO-α	Growth-regulated oncogene α
ARRIVE	Animals in Research Reporting In Vivo Experiments
SYRCLE	Systematic Review Centre for Laboratory animal Experimentation
TRAIL	TNF-related apoptosis-inducing ligand
NOV	Nephroblastoma overexpressed
PCNA	Proliferating cell nuclear antigen
ADAMTS	A disintegrin and metalloproteinase with thrombospondin motifs