Table 2.

Potential predictive and/or prognostic biomarker in HNSCC.

miRNA	Regulation	Cancer	Diagnosis/Prognosis	Ref.
Let-7a	Up	LCa	Diagnosis	[101]
Let-7g	Up	OSCC	Prognosis	[113]
miR-100	Down	HNSCC	Prognosis	[117]
miR-101	Down	LCa	Prognosis	[108]
miR-10b	Up	OSCC	Diagnosis	[44]
miR-125b	Up	OSCC	Prognosis	[113]
miR-125b	Down	HNSCC	Prognosis	[117]
miR-1287	Down	LCa	Diagnosis	[97]
miR-1303	Up	LCa	Diagnosis	[99]
miR-133b	Down	LCa	Diagnosis	[96]
miR-143	Down	OSCC	Prognosis	[116]
miR-145	Down	OSCC	Prognosis	[116]
miR-146a	Down	HNSCC	Diagnosis	[50]
miR-155	Up	OSCC	Prognosis	[48,49]
miR-15a	Down	HNSCC	Diagnosis, Prognosis	[117]
miR-181a	Down	SACC, TSCC	Prognosis	[53,126]
miR-196a	Up	LCa, OSCC	Diagnosis	[96,105]
miR-196b	Up	OSCC	Diagnosis	[105]
miR-199b	Down	HNSCC	Diagnosis, Prognosis	[117]
miR-200a	Down	LCa	Prognosis	[111]
miR-200c	Down	LCa	Prognosis	[111]
miR-203	Up	HNSCC	Prognosis	[54]
miR-203	Down	HNSCC	Prognosis	[121]
miR-204	Down	OSCC	Prognosis	[88]
miR-205	Down	HNSCC	Prognosis	[102]
miR-205	Up	HNSCC	Prognosis	[112]
miR-205-5p	Down	OSCC	Diagnosis, Prognosis	[103]
miR-21	Up	HNSCC	Prognosis	[114,117]
miR-21	Up	LCa	Diagnosis, Prognostic	[94,95]
miR-212-3p	Up	LCa	Diagnosis	[99]
miR-218	Up	OSCC	Prognosis	[113]
miR-223	Up	HNSCC	Prognosis	[114]
miR-23a	Up	LCa	Prognosis	[107]
miR-296-5p	Up	LCa	Prognosis	[110]
miR-31	Up	LCa	Diagnosis	[101]
miR-33	Up	LCa	Diagnosis	[101]
miR-331-3p	Up	LCa	Diagnosis	[99]
miR-34c	Down	HNSCC	Diagnosis, Prognosis	[117]
miR-375	Down	LCa	Diagnosis, Prognosis	[95]
miR-375	Down	LCa	Diagnosis	[98]
miR-378	Up	LCa	Diagnosis	[100]
miR-455-5p	Up	LCa	Diagnosis	[96]
miR-603	Up	LCa	Diagnosis	[99]
miR-657	Up	LCa	Diagnosis	[97]
miR-9	Up	LCa	Prognosis	[109]
miR-9	Down	OSCC	Prognosis	[118]
miR-93	Up	HNSCC	Prognosis	[28,115]
miR-99a	Down	HNSCC	Prognosis	[114]

HNSCC: Head and neck squamous cell carcinoma; LCa: Laryngeal cancer; OSCC: Oral squamous cell cancer; SACC: Salivary adenoid cystic carcinoma; TSCC: Tongue squamous cell carcinoma.