Figure 1.

Damage following Rose Bengal (RB) photothrombosis in perinatal rat model. (a) Experimental design for animal model. Photothrombosis is achieved via intraperitoneal injection of RB (25 mg/kg) and illumination (532 nm, 36 mV) of the sensory-motor cortex through a cranial window. (b) Representative photographs of coronal brain sections stained with 2,3,5-TriphenylTertrazoium Chloride (TTC) and whole-brain at one day after modeling. The lack of formazan production (white tissue) indicates an infarct area with a white line. Quantification of (c) infarct volume and (d) wire hang test. Data represented as mean ± SD. * p < 0.01 compared with the control group.