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Compound octanol/water partition (logP) values and solvent-accessible surface area for docked poses in PKCα isoform.
| Compound | Total Solvent Accessible Area (Å2) | Solved Exposed Area in Docked Pose (Å2) | Exposed Surface Ratio % | logP |
|---|---|---|---|---|
| DeRoy (1) | 268.47 | 142.36 | 53.02 | 4.53 |
| Roy (2) | 318.47 | 209.29 | 65.71 | 2.65 |
| ParvD (3) | 171.75 | 355.37 | 48.12 | 5.64 |
| RoyBz (4) | 469.79 | 260.01 | 55.35 | 7.88 |
| RoyBzCl (5) | 504.92 | 323.30 | 64.03 | 8.8 |
| RoyPr2 (6) | 403.77 | 207.97 | 51.50 | 4.87 |
| DihidroxyRoy (7) | 285.37 | 165.58 | 58.02 | 2.52 |
