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. 2020 Apr 30;10(5):870. doi: 10.3390/nano10050870

Table 3.

Glycyrrhizin/glycyrrhetinic acid chitosan nanoparticles for the treatment of HCC and liver-targeting: the therapeutic/theranostic effect and cell cultures used in the study are reported for each reference.

Carrier Payload Effect Cell Culture Reference
Glycyrrhizin chitosan - liver targeting hepatocytes [81]
Glycyrrhizin chitosan lamivudine anti-retroviral - [82]
Glycyrrhizin chitosan atorvastatin reduction in hepatotoxicity - [83]
Glycyrrhetinic acid chitosan/PEG doxorubicin anti-cancer H22;
QGY-7703
[84]
Glycyrrhizin N-caproyl chitosan - liver targeting H22; SMMC-7721 [85]
Glycyrrhizin O-CM chitosan paclitaxel anti-cancer SMMC-7721 [86]
Glycyrrhetinic acid galactose chitosan mouse IP-10 gene liver targeting - [87]