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. 2020 May 1;10(5):875. doi: 10.3390/nano10050875

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the mechanism of action of calcium phosphate (CaP) coated nanoparticles (NPs) loaded with antibiotic. Negatively charged NPs could selectively bind Ca²⁺ ions situated on bone surface.