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. 2020 May 1;10(5):875. doi: 10.3390/nano10050875

Table 8.

Traditional materials used for bone repair [33].

Material Type of material Advantages Disadvantages
Bone Autologous bone Biocompatible with high bone fusion rate Limited sources
Allogenic bone Relatively high bone fusion rate Immune rejection
Heterologous bone Wide variety of sources Severe immune rejection and poor bone formation
Bone cement Non-bioactive bone cement Easy fit, good hardening properties Poor biocompatibility, non-osteoinductive, non-osteoconductive
Bioactive bone cement High strength, stability and bone induction activity Insufficient mechanical properties, expensive
Metal Stainless steel Easy processing, inexpensive High stiffness, poor biocompatibility
Titanium alloy Biocompatible, corrosion resistance Poor wear resistance
Cobalt chromium alloy Biocompatible, high corrosion resistance Low ductility
Ceramic Aluminium oxide Inertness, high corrosion resistance Possible local stress
Apatite-wollas-tonite glass ceramic Good biological activity Brittleness, poor flexibility
Polymer Poly(lactic-co-glycolic) acid (PLGA) Biocompatible, degradable Possible disruption
PMMA Corrosion resistance, easy fit Poor biocompatible
Chitosan High degradable and biocompatible, porous structure, good mechanical properties Non-osteoinductive, inadequate bone formation ability, low solubility
Alginate Easy to manipulate, non-toxic, biodegradable, less expensive Low mechanical stability