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. 2020 May 20;21(10):3620. doi: 10.3390/ijms21103620

Figure 2.

Figure 2

Inflammatory cytokine mRNA expression in the femur. The mRNA expression of inflammatory cytokines in the femurs was quantified using RT-PCR (n = 6 per group). The inflammatory cytokines TNF-α, IL-6, IL-1α, IL-1β, IL-17A, and IL-23a were measured and standardized using GAPDH. In the KCASP1Tg mice, TNF-α expression was significantly increased (A) and IL-1α expression decreased (C). There was no difference in the expression of IL-6, IL-1β, or IL-23a (B,D,F), and IL-17A was undetectable (E). All data are expressed as mean ± SD. N.D: not detected; **: p < 0.01 between KCASP1Tg and wild-type mice by Mann–Whitney test.