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Renal function and tubular damage at 24 h in renal ischaemia/reperfusion injury (IRI) and sham controls for wild type (WT; closed circles) and CypA−/− (open circles) mice. (A) RT-PCR analysis of CypA mRNA levels in WT mice. (B) Serum creatinine levels. (C) Graph of tubular damage. (D) Periodic acid-Schiff stained kidney sections from each group. Bar = 200 μm. Data are mean ± SD. *** p < 0.001 versus WT sham control.
