Table 1.

Prognosis for various types of cancer with increased expression of CX3CL1 or CX3CR1 according to reports available in PubMed.

Type of Cancer	Prognosis at Increased Expression of a Given Protein in Tumor	Number of Patients in the Study	Comments	Source
CX3CL1
Colorectal cancer	↓	174	Plasma samples	[113]
Colorectal Cancer	↑	100	Co-expression of CX3CL1 and CX3CR1	[79]
Colorectal Cancer	↑	50		[71]
Breast cancer	↓	753		[76]
Breast carcinoma	↑	204		[74]
Gastric adenocarcinoma	↑	158		[73]
Glioma	↑	61		[78]
Grades III–IV brain tumours	↓	36		[110]
Hepatocellular carcinoma	↑	56	Co-expression of CX3CL1 and CX3CR1	[109]
Lung adenocarcinoma	↑	--	From The Cancer Genome Atlas	[80]
Lung adenocarcinoma	↓	41	Patients with smoking history	[111]
Pancreatic ductal adenocarcinoma	↓	105		[112]
Soft tissue sarcomas	↑	69	Female	[81]
CX3CR1
Clear cell renal cell carcinoma	↓	78		[46]
Colorectal Cancer	↑	100	Co-expression of CX3CL1 and CX3CR1	[79]
Hepatocellular carcinoma	↑	56	Co-expression of CX3CL1 and CX3CR1	[109]
Epithelial ovarian carcinoma	↓	557		[21]
Pancreatic ductal adenocarcinoma	↓ p = 0.059	105		[112]
Pancreatic ductal adenocarcinoma	↑	104		[20]

↑—better prognosis; ↓—worse prognosis; --—no correlation