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. 2020 May 25;21(10):3728. doi: 10.3390/ijms21103728

Figure 3.

Figure 3

Effects of experimentally induced chronic immobilization stress and ligature-induced periodontitis on RANK and RANK-L expression of the alveolar bone (blue arrows) of male Wistar rats (90-days-old, n = 28). Representative photomicrographs of the control group; experimental periodontitis group (EP); chronic stress group (CS); and chronic stress and experimental periodontitis group (CS+EP). Results are expressed as mean ± standard error of immunohistochemistry score (IHC score) of RANK and RANKL expression. Kruskal–Wallis test, p < 0.05. Similar overwritten letters did not reveal statistically significant differences. EP: ligature-induced experimental periodontitis group; CS: chronic stress by physical restraint model; CS+EP: association of chronic stress and ligature-induced periodontitis. Scale bar: 100 µm. Cementum (★) and periodontal ligament (*).