Table 2.
List of formulations used for the preparation of magneto-liposomes (MLs) with corresponding physicochemical properties. Hydrodynamic size, polydispersity index (PDI) and zeta potential as determined using dynamic light scattering (DLS). Fe content in MLs as measured using inductively coupled plasma mass spectrometry (ICP-MS).
| Lipid Formulation | Size (nm) | PDI | ζ-Potential (mV) | Fe (µg/mL) |
|---|---|---|---|---|
| DOPC/DSPE-PEG2000 (96/4) | 144 ± 3 | 0.09 ± 0.01 | −0.6 ± 0.2 | 0.50 ± 0.03 |
| DPPC/DSPE-PEG2000 (96/4) | 150 ± 4 | 0.10 ± 0.04 | 0.8 ± 0.3 | 5.32 ± 0.08 |
| DSPC/DSPE-PEG2000 (96/4) | 135 ± 2 | 0.11± 0.05 | −0.4 ± 0.2 | 15.90 ± 0.10 |
| DOPC/Chol/DSPE-PEG2000 (96/50/4) | 156 ± 4 | 0.10 ± 0.02 | −0.5 ± 0.2 | 0.65 ± 0.05 |
| DPPC/Chol/DSPE-PEG2000 (96/50/4) | 155 ± 6 | 0.11 ± 0.03 | 1.9 ± 0.2 | 1.22 ± 0.08 |
| DSPC/Chol/DSPE-PEG2000 (96/50/4) | 141 ± 5 | 0.07 ± 0.01 | 0.3 ± 0.1 | 1.76 ± 0.08 |