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MLs as a promising MRI T2 contrast agent. Calculated longitudinal (r1) and transverse (r2) relaxivities of different MLs and HCA-IO NPs.
| Sample | r1 (mM−1 s−1) | r2 (mM−1 s−1) |
|---|---|---|
| DOPC/DSPE-PEG2000 (96/4) | <0.5 | 673 ± 12 |
| DPPC/DSPE-PEG2000 (96/4) | <0.5 | 283 ± 9 |
| DSPC/DSPE-PEG2000 (96/4) | <0.5 | 156 ± 4 |
| DOPC/Chol/DSPE-PEG2000 (96/50/4) | <0.5 | 575 ± 5 |
| DPPC/Chol/DSPE-PEG2000 (96/50/4) | 0.6 ± 0.1 | 153 ± 5 |
| DSPC/Chol/DSPE-PEG2000 (96/50/4) | <0.5 | 389 ± 9 |
| HCA-IO NPs | 0.4 ± 0.1 | 16 ± 3 |
