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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Antiviral Res. 2020 Feb 17;176:104749. doi: 10.1016/j.antiviral.2020.104749

Figure 4: Mode of anisomycin antiviral action.

Figure 4:

Vero cells were exposed to 100 PFU of (A) DENV-2 or (C) ZIKV during 1 h at 4°C, then covered with MM in presence or absence of anisomycin (200 nM) and transferred to 37°C. At the indicated times, non-internalized virus was inactivated and internalized particles were determined by plaque assay. Data are mean values from three independent experiments ± SD. (B) DENV-2 or (D) ZIKV infected Vero cells (MOI= 1) were treated with anisomycin (200 nM) and at different times p.i., cells expressing viral E glycoprotein were detected by an immunofluorescence assay. Cell nuclei were stained with Hoechst. Magnification 100x.