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. 2019 Nov 12;73(6):350–352. doi: 10.1136/jclinpath-2019-206261

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Histology images and potential pitfalls and advantages of WSI (all figures represent original images without postprocessing). (A) routine quality of H&E frozen sections slides using robotic microscopy and the iPath system (basal cell carcinoma); (B) routine quality of the same H&E frozen section slide using uPath; (C) case with many folds, in which the IMS managed to correctly focus on the thin evaluable areas without the need of further manual readjustment (sentinel lymph node); (D) case with a focus issue in one of the serial sections: while the left half of the tissue is focused correctly, the right half is out of focus; the second serial section was entirely focused (basal cell carcinoma of B). IMS, image management software; WSI, whole slide imaging.