Table 1.
Patient characteristics
| Characteristic | NTX-010 n = 26 | Placebo n = 24 | Overall n = 50 | p-value |
|---|---|---|---|---|
| Age, Median (Range) | 67 (44–81) | 60 (50–82) | 63 (44–82) | 0.18 |
| Sex, n (%) | 0.41 | |||
| Female | 12 (46.2) | 14 (58.3) | 26 (52.0) | |
| Male | 14 (53.9) | 10 (41.7) | 24 (48.0) | |
| Ethnicity, n (%) | 1.00 | |||
| Non-Hispanic | 24 (92.3) | 24 (100) | 48 (96.0) | |
| Not Reported | 1 (3.9) | 0 (0.0) | 1 (2.0) | |
| Unknown | 1 (3.9) | 0 (0.0) | 1 (2.0) | |
| Performance Status, n (%) | 1.00 | |||
| 0 | 8 (30.8) | 7 (29.2) | 15 (30.0) | |
| 1 | 18 (69.2) | 17 (70.8) | 35 (70.0) | |
| Smoking Status, n (%) | 0.34 | |||
| Never smoked | 0 (0.0) | 2 (8.3) | 2 (4.0) | |
| Current smoker | 7 (26.9) | 4 (16.7) | 11 (22.0) | |
| Former smoker | 19 (73.1) | 18 (75.0) | 37 (74.0) | |
| Prior Response to Chemotherapy, n (%) | 0.80 | |||
| Stable Disease | 4 (15.4) | 5 (20.8) | 9 (18.0) | |
| Partial Response | 15 (57.7) | 12 (50.0) | 27 (54.0) | |
| Complete Response | 7 (26.9) | 7 (29.2) | 14 (28.0) | |
| Time Between Completion of Chemotherapy to Randomization, n (%) | 0.93 | |||
| 1 month | 10 (38.5) | 9 (37.5) | 19 (38.0) | |
| 2 months | 10 (38.5) | 10 (41.7) | 20 (40.0) | |
| 3 months | 6 (23.1) | 4 (16.7) | 10 (20.0) | |
| Unknown | 0 (0.0) | 1 (4.2) | 1 (2.0) | |
| Prior CNS Radiation Therapy, n (%) | 0.77 | |||
| Yes | 8 (30.8) | 9 (37.5) | 17 (34.0) | |
| No | 18 (69.2) | 15 (62.5) | 33 (66.0) | |