Table 4. Analysis of the correlation between mRNA and protein expression levels of PI3K, mTOR, RhoA, p-RhoA protein, and mean fluorescence intensity (MFI) and percent phagocytosis (r value).
Index/Group | PI3K | mTOR | RhoA | p-RhoA protein | |||
---|---|---|---|---|---|---|---|
mRNA | Protein | mRNA | Protein | mRNA | Protein | ||
MFI | |||||||
Blank control | 0.92* | 0.93** | - 0.83* | - 0.91* | 0.95** | 0.84* | 0.86* |
Negative control | 0.93** | 0.92** | - 0.92* | - 0.91* | 0.89* | 0.98** | 0.91* |
PI3K-RNAi | 0.90* | 0.84* | - 0.85* | - 0.87* | 0.85* | 0.92* | 0.88* |
mTOR-RNAi | 0.93** | 0.85* | - 0.83* | - 0.91* | 0.92** | 0.98** | 0.90* |
Phagocytosis (%) | |||||||
Blank | 0.95** | 0.93** | -0.89* | -0.97** | 0.95** | 0.96** | 0.97** |
Negative control | 0.94** | 0.82* | -0.96** | -0.94** | 0.99** | 0.90* | 0.97** |
PI3K-RNAi | 0.99** | 0.90* | -0.88* | -0.92* | 0.96** | 0.97** | 0.90* |
mTOR-RNAi | 0.99** | 0.82* | -0.87* | -0.98** | 0.94** | 0.92** | 0.90** |
*P<0.05, **P<0.01 (Pearson's linear correlation analysis).