Figure 3. The re-distribution of CD68+ TAMs and Ly6G+ PMN-MDSCs around PIMO+ chronically hypoxic areas. Representative section of TRAMPC1 tumors stained for hypoxia, CD31, CA9, CD68 and Ly6G in (A) VE7D and (B) SU9D tumors (bar: 100 μm). (C) Quantitative comparison of the Ly6G+ PMN-MDSCs population within the necrotic region in size-matched VE7D and SU9D tumors. (D) Quantitative comparison of CD68+ TAMs population within hypoxic regions in size-matched VE7D and SU9D tumors.