Figure 1. The effect of wogonin on CD133+ Cal72 cell viability and proliferation. Assays revealed a dose-dependent reduction of viability of wogonintreated CD133+ Cal72 cells. A: Two-dimensional structure of wogonin. B: Cytotoxicity assay. C: Cell proliferation. D: Western blotting showed dosedependent reduction of survivin expression as on inhibitor of apoptotic activation. ***Significantly different from control cells at p<0.001.