FIGURE 8.

Antegrade axoplasmic flow in the optic nerve head at 8 weeks after streptozotocin injection. In the diabetes group, some antegrade axoplasmic flow was blocked in the lamina region (arrow) compared to that in the normal control group. The overall expression of cholera toxin subunit B was lower in the diabetes group than the control group (n = 5 per group). The blockade of antegrade axoplasmic transport was partly alleviated with combined latanoprost and brinzolamide treatment (n = 5 per group). *P < .05, significantly different as indicated; Kruskal–Wallis and post hoc Dunn's test (one‐tailed)