Fig. 1. Increases in mean resting regional cerebral blood flow (rCBF) in the anterior cingulate, right insula, orbitofrontal and medial prefrontal cortices in BN/BED women compared with healthy women (hypothesis-driven analysis).

These graphs illustrate the changes in mean rCBF in BN/BED patients compared with healthy controls for the regions-of-interest where we identified a significant main effect of diagnosis. For all of these four regions-of-interest, BN/BED women presented higher mean rCBF than healthy women. ACG anterior cingulate gyrus, OFC orbitofrontal cortex, PFC medial prefrontal cortex. Box plots and violin plots depicting mean rCBF (marginal means) on each region-of-interest for each diagnosis/treatment groups; middle horizontal lines represent the median; boxes indicate the 25th and 75th percentiles.