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. 2019 Oct 26;393(3):491–500. doi: 10.1007/s00210-019-01749-5

Fig. 3.

Fig. 3

Effect of CG200745 on HDAC activity in the kidney of ND- and HFD-fed mice. Graphs summarize kidney HDAC activity and mRNA expressions of HDAC 1, 2, 3, and 6. HDAC activities were increased by HFD and reversed by CG200745 to the ND level. mRNA expressions of HDAC 1, 2, 3, and 6 were increased by HFD but not decreased by CG200745. Results are expressed as the mean ± SE (n = 5–8 mice per group). HDAC, histone deacetylase; ND, normal diet; HFD, high-fat diet; Veh, vehicle; CG, CG200745