Skip to main content
. 2019 Oct 26;393(3):491–500. doi: 10.1007/s00210-019-01749-5

Fig. 4.

Fig. 4

Effect of CG200745 on renin-angiotensin system in the ND- or HFD-fed mice. Graphs summarize kidney mRNA expression of angiotensinogen (a), protein expression of angiotensinogen and representative picture of western blot (b), serum concentration of Ang II (c), kidney mRNA expression of renin (d), lung mRNA expression of ACE (e). a–e Renin-angiotensin system components were increased by HFD and reversed to the normal level by CG200745 treatment. Results are expressed as the mean ± SE (n = 3–5 mice per group). ND, normal diet; HFD, high-fat diet; Veh, vehicle; CG, CG200745; Ang II, angiotensin II; ACE, angiotensin-converting enzyme