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. 2020 Jun 8;11(6):434. doi: 10.1038/s41419-020-2633-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — FOXC2-AS1 knockdown significantly suppressed CRC cell migration and invasion, as detected by wound healing (a) and Transwell assay (b). The data statistics of wound-healing assay (c) and Transwell assay. d The effect of FOXC2-AS1 on CRC liver metastasis in vivo, the metastatic nodules in liver tissue were detected by HE staining (e), and data statistics of metastatic nodules (f). Scale bars = 100 μm *P < 0.05, **P < 0.01.