Table 1.
Correlation between IDH1 mutation and MRI features of glioma.
| MRI features | All | P-value |
Low grade |
P-value |
High grade |
P-value |
|---|---|---|---|---|---|---|
| Pattern of growth | ||||||
| Unilateral | 61/113 | 0.902 | 51/55 | 0.929* | 10/58 | 0.692* |
| Bilateral | 1/3 | 1/1 | 0/2 | |||
| Tumor margins | ||||||
| Sharp | 13/25 | 0.869 | 13/14 | 0.549 | 0/11 | 0.2326 |
| Indistinct | 49/91 | 39/42 | 10/49 | |||
| Signal intensity | ||||||
| Homogeneous | 46/20 | 0.009 | 16/17 | 0.747 | 0/3 | 0.573* |
| Heterogeneous | 16/96 | 36/39 | 10/57 | |||
| Contrast enhancement | ||||||
| Absent or slight | 48/57 | 0.000 | 46/50 | 0.627* | 2/7 | 0.719 |
| Significant | 14/59 | 6/6 | 8/53 | |||
| Mass effect | ||||||
| Absent or moderate | 24/41 | 0.416 | 23/26 | 0.504 | 1/15 | 0.424 |
| Severe | 38/75 | 29/30 | 9/45 | |||
| Edema | ||||||
| Absent or moderate | 27/47 | 0.476 | 26/28 | 0.604 | 1/19 | 0.215 |
| Severe | 35/69 | 26/28 | 9/41 | |||
| Cross the midline | ||||||
| Yes | 4/8 | 0.001 | 3/3 | 0.797* | 1/5 | 1.000* |
| No | 58/108 | 49/53 | 9/55 | |||
| Under the ependyma | ||||||
| Yes | 33/55 | 0.115 | 23/25 | 0.765 | 10/30 | 0.001 |
| No | 29/61 | 29/31 | 0/30 | |||
| Diameter of tumor | ||||||
| ≥5 cm | 24/46 | 0.978 | 18/19 | 0.874 | 6/27 | 0.486 |
| <5 cm | 38/70 | 34/37 | 4/33 | |||
*
Fisher's exact probability test.