Figure 4.
A bar chart displaying the simulated lung peak plasma concentration (Cmax)/half‐maximal effective concentration (EC50). Drugs with a ratio below 1 were deemed not to provide lung concentrations at their approved doses to exert sufficient pulmonary antiviral activity for treatment or prevention strategies. Those drugs with a ratio above 1 (shown in orange) were estimated to provide lung concentrations sufficient to exert at least some antiviral activity at their approved dose. Drugs shown in green were predicted to exceed lung concentrations over their EC50 by > 10‐fold.