Table 3.
Clinical characteristics
| Overall (N = 151) | |
|---|---|
| First non-Raynaud’s symptom | |
| Hand swelling/puffy hands | 88 (58.3%) |
| Skin tightening | 19 (12.6%) |
| Arthralgia, arthritis | 13 (8.6%) |
| Dyspnea | 9 (6.0%) |
| Other1 | 22 (14.6%) |
| Patient ever had diffuse involvement | |
| Yes | 90 (59.6%) |
| No | 61 (40.4%) |
| ANA2 | |
| Negative | 11 (7.3%) |
| Positive | 130 (86.1%) |
| Unavailable | 10 (6.6%) |
| Anti-Centromere | |
| Negative | 99 (65.6%) |
| Positive | 13 (8.6%) |
| Unavailable | 39 (25.8%) |
| Anti-SCL 70 | |
| Negative | 83 (55.0%) |
| Positive | 51 (33.8%) |
| Unavailable | 17 (11.3%) |
| Anti-Polymerase III | |
| Negative | 77 (51.0%) |
| Positive | 35 (23.2%) |
| Unavailable | 39 (25.8%) |
| SSc-specific antibody positive (Anti Centromere, Anti SCL 70 or Anti Polymerase III positive) | |
| Yes | 97 (64.2%) |
| No | 44 (29.1%) |
| Unavailable | 10 (6.6%) |
1
Other includes digital ulcer, reflux, leg swelling, carpal tunnel syndrome, GI symptoms (other than reflux) and other
2
ANA, anti-nuclear antibody