Figure 6.

Ceramide (Cer) accumulation in glomeruli of Asah1^fl/fl/Podo^Cre mice. A: Representative multiple reaction monitoring chromatography of ceramides separated by liquid chromatography–tandem mass spectrometry. B: Summarized data showing the levels of C16 ceramide in isolated glomeruli of different groups of mice. C: Summarized data showing the levels of total ceramide in isolated glomeruli of different groups of mice. D: Summarized data showing the levels of sphingosine (Sph) in isolated glomeruli of different groups of mice. n = 4 to 6 (B–D). ∗P < 0.05 versus WT/WT. cps, counts per second; Cre, Cre recombinase.