Fig. 1.

Peptide induced changes in composition of cell populations: Heatmap showing fold change of subsets of CD4+ and CD8+ T cells induced by RSV-peptide re-stimulation (first horizontal bar) compared to the DMSO treatment across the three visits: V1, V2, and V3. The proportions of the cell subsets were calculated using the number of CD4+ or CD8+ T cells as parents. The colors depict fold difference calculated by dividing the proportion of the cell subsets observed upon stimulation with the proportion observed upon DMSO stimulation. Note that the values <1 correspond to a smaller value than DMSO. Fold difference that is between 0.9 and 1.1 is in white, indicating a minor change from DMSO. A generalized linear mixed effect regression analysis model is applied to generate p-values after Benjamini-Hochberg (BH) correction to indicate the significance of the difference with BH-adjusted p-value cutoff = 0.05. * indicates a significant change with p-value < 0.05.