Table 6.
Cox proportional hazard regression analysis for 28-day mortality in SIC patients and sepsis patients as a whole
| Variable | Univariate |
Multivariate |
||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| SIC patient | ||||
| APACHE II | 1.08 (1.02–1.14) | 0.006 | 1.10 (1.02–1.18) | 0.009 |
| DNI | 1.03 (0.01–2.21) | 0.027 | 1.02 (1.00–1.08) | 0.026 |
| Lactate | 1.12 (1.01–1.24) | 0.036 | 1.12 (0.74–1.07) | 0.210 |
| EF | 0.97 (0.91–1.04) | 0.381 | ||
| LVEDD | 0.94 (0.85–1.04) | 0.231 | ||
| Sepsis patients as a whole | ||||
| APACHE II | 1.06 (1.03–1.09) | <0.001 | 1.04 (1.01–1.07) | 0.004 |
| DNI | 1.03 (0.01–1.04) | <0.001 | 1.02 (1.00–1.03) | 0.044 |
| Lactate | 1.12 (1.07–1.16) | <0.001 | 1.07 (1.02–1.13) | 0.007 |
| EF | 1.01 (0.99–1.03) | 0.321 | ||
| LVEDD | 0.96 (0.93–0.98) | 0.008 | 0.97 (0.93–1.01) | 0.118 |
| SIC | 0.89 (0.0.48–1.65) | 0.723 | 0.88 (0.43–1.74) | 0.688 |
SIC: sepsis-induced cardiomyopathy; HR: hazard ratio; CI: confidential interval; APACHE: Acute Physiology and Chronic Health Evaluation; DNI: delta neutrophil index; EF: ejection fraction; LVEDD: left ventricular enddiastolic diameter.