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. 2020 Jun 9;20:100367. doi: 10.1016/j.imu.2020.100367

Table 1.

List of plant metabolites used in the study with respective source and activities.

Metabolites PubChem CID Class Source Activities References
Allicin 65036 S-containing compound Allium sativum Antimicrorial, antiviral Antioxidant, anti-cancer activity [25]
Andrographolide 5318517 Diterpenoid labdane Andrographis paniculata antioxidant, anti-inflammatory, and anti-cancer [26]
Apigenin 5280443 Flavonoid Vegetable and fruit Effective in cancer, depression, diabetes & Alzheimer's disease, [27]
Asiatic acid 119034 Aglycone type pentacyclic triterpenoids Centella asiatica Antioxidant, cardioprotective, anti-inflammatory, antitumor, neuroprotective, antimicrobial [28]
Avicularin 5490064 quercetin-3-a-L arabinofuranoside (flavonoid) Psidium guyava, Lespedeza cuneata anti-inflammatory, anti-oxidant, hepatoprotective activity [29]
Capsaicin 1548943 Alkaloid Capsicum genus Pruritis, pain relief, non-steroidal anti-inflammatory drug induced gastritis [30]
Chavibetol 596375 Phenylpropanoid Piper betle immunomodulatory, radical scavenging [31]
Cinnamic acid 444539 Aromatic carboxylic acids Cinnamomum species Antibacterial, antifungal, antimalarial, antitubercular [32]
Curcumin 969516 Polyphenolic compound Curcuma longa antibacterial, anti-inflammatory antiviral, antioxidant, anti-arthritis & anti-cancer activity [33]
Eugenol 3314 Phenylpropanoid Ocimum tenuiflorum, Eugenia caryophyllata antimicrobial, anti-inflammatory, analgesic and antioxidant [34]
Arjunone 14034821 Flavonoids Terminalia arjuna Arjunone and other compounds have role in antioxidant, antiatherogenic, anti-inflammatory, anti-carcinogenic activity [35]
Galangin 5281616 Flavonol Honey, Alpinia officinarum, propolis Anti-cancer, anti-mutagenic, anti-oxidative, radical scavenging etc. [36]
Gentisic acid 3469 Phenolic acid Gentiana, Citrus, H. rosa-sinensis,
O. europaea, S. indicum
Antioxidant, neuroprotective, antiinflammatory, hepatoprotective, antimicrobial activities [37]
Guajaverin 5481224 Flavonoid Psidium guyava Anti-plaque activity [38]
Kaempferol 5280863 Flavonoid aglycone Vegetable and fruit Anti-inflammatory, antioxidant, antimicrobial, antitumor, cardioprotective, and antidiabetic activities [39]
Luteolin 5280445 Flavonoid Carrots, celery peppers, olive peppermint Anticancer, antioxidant, antimicrobial, anti-inflammatory, and activities [40]
m-Coumaric acid 637541 Phenolic acid Solanum nigrum Role in pharmacological activities [41]
Piperic acid 5370536 Alkaloid Piper nigrum No known function [42]
Piperine 638024 Alkaloid Piper spp. Anticancer, antimicrobial, antimalarial [42]
Quercetine 5280343 Flavonoid Diverse plant species Antioxidant, cardiovascular, antiviral, anti-inflammatory, anticancer, antimicrobial [43]
Swertiamarin 442435 Secoiridoid glycoside Swertia chirata Anti-arthritic, anti-diabetic Cardio-protective, Anticancer, Anti-hepatitis, Antibacterial, anti-atherosclerotic [44]
Swertinin 5491517 Secoiridoid glycoside Swertia chirata Role in pharmacological activities [45]
Thymoquinone 10281 Monoterpene Nigella sativa Anti-oxidant and anti-inflammatory properties, Anti-microbial, Anti-arthritic, anti-cancer efficacy [46]
Vincamine 15376 Alkaloid Catharanthus roseus, Vinca minor Cerebral disorders, antiulcer activity, cerebrovascular insufficiencies [47]
Vitexin 5280441 Apigenin flavone glucoside Crataegus species Anti-inflammatory effects, anti-oxidant effects, anti-carcinogenic effects, anti-viral effects [48]
Withaferin 265237 Steroidal lactone Withania somnifera Anti-cancer, adaptogenic, anti-stress, immunomodulatory, anti-inflammatory, anti-tumor, cardioprotective, and neuroprotective activities. [49]
Zingiberene 92776 Isoprenoids Zingiber Officinale Anti-ulcer, antibacterial, cytoxic effect [50]