Figure 6.

(a) Lateral deterministic migration-based WBC separation using the low aspect ratio straight microchannel with discontinuous slant array (DSA) [100]. Adapted with permission from Kim et al. (b) High-throughput, sheathless, magnetophoretic sorting of magnetic and nonmagnetic particles using the grooved microchannel [101]. Adapted with permission from Yan et al. (c) Three-dimensional, sheathless and high-throughput particle single-streamline focusing method using the stepped microchannel [102]. Adapted with permission from Chung et al. (d) Sheathless, high-throughput and three-dimensional particle-focusing method using a double-layered microfluidic device consisting of the low aspect ratio straight channel and arc-shaped groove array pattern on the top surface [103]. Adapted with permission from Zhao et al. (e) Enhanced sheath flow-assisted particle-focusing and separation method eliminating size limitation of conventional design [104]. Adapted with permission from Zhao et al.